Journal article
Purinergic modulation of neural control of cardiac function
Journal of autonomic pharmacology, v 16(6), pp 401-406
Dec 1996
PMID: 9131426
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
1. The purine nucleotide adenosine 5'-triphosphate (ATP) and its related nucleoside, adenosine (Ado), exert pronounced electrophysiologic, inotropic, lusitropic and metabolic effects in the mammalian heart. 2. These effects are the result of direct actions of these compounds on cardiac myocytes and endothelial cells, mediated by cell surface receptors. 3. In addition, ATP and Ado can stimulate neural elements inside and outside the heart and thereby modulate neural control of cardiac function. These latter actions of ATP and Ado are briefly reviewed and their hypothetical physiological role is outlined.
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Details
- Title
- Purinergic modulation of neural control of cardiac function
- Creators
- A Pelleg - Allegheny University of the Health SciencesG Katchanov - Allegheny University of the Health SciencesJ Xu - Allegheny University of the Health Sciences
- Publication Details
- Journal of autonomic pharmacology, v 16(6), pp 401-406
- Publisher
- Wiley
- Grant note
- 43006 / PHS HHS
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:A1996WU20200026
- Scopus ID
- 2-s2.0-0030433684
- Other Identifier
- 991019348911804721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Neurosciences
- Pharmacology & Pharmacy