Published, Version of Record (VoR)CC BY V4.0, Open
Abstract
Life Sciences & Biomedicine Radiology, Nuclear Medicine & Medical Imaging Science & Technology
OBJECTIVE. Breast cancer is the most frequent type of cancer among women (25% of all cancers). The angiogenic process that fuels the growth of tumors is a potential early indicator for differentiating between malignant and benign tumors. Recently, the use of microbubble-based contrast agents combined with ultrasound has allowed the development of contrast agent-specific imaging modes that provide visualization of tumor neovascularity.
CONCLUSION. Contrast-enhanced Doppler, harmonic, and subharmonic imaging are some of the imaging modes that have been investigated for visualizing and quantifying the vascularity in breast tumors.