Journal article
Racial and Geographic Differences in Prevalence, Awareness, Treatment and Control of Dyslipidemia: The Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study
Neuroepidemiology, v 37(1), pp 39-44
01 Jan 2011
PMID: 21822024
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background/Aims: There are racial and geographic disparities in stroke mortality, with higher rates among African Americans (AAs) and those living in the southeastern US ('stroke belt'). Racial and geographic differences in dyslipidemia prevalence, awareness, treatment and control may, in part, account for the observed disparities in stroke mortality. Methods: Reasons for Geographic and Racial Differences in Stroke (REGARDS) is a national observational study of community-dwelling black and white participants aged 45 and older, with oversampling from the stroke belt. As of January 15, 2007, 26,122 participants were enrolled and a fasting lipid panel was available of 21,068. Awareness, treatment and control of dyslipidemia were estimated overall and compared across race-sex-region strata. Results: There were 55% of the participants with dyslipidemia and no racial differences in prevalence. Adjusting for demographic and established stroke risk factors, AAs had a lower prevalence (OR 0.74; 95% CI: 0.66, 0.77) and were less likely to be aware (0.69; 0.61, 0.78), treated (0.77; 0.67, 0.89) and controlled (0.67; 0.58, 0.77) than whites. There was lower control outside of the stroke belt (0.87; 0.76, 0.99). Conclusion: Racial, but not geographic, differences in dyslipidemia management may play a role in the excess stroke burden in the Southeast. Copyright (C) 2011 S. Karger AG, Basel
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Details
- Title
- Racial and Geographic Differences in Prevalence, Awareness, Treatment and Control of Dyslipidemia: The Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study
- Creators
- Richard M. Zweifler - Eastern Virginia Medical SchoolLeslie A. McClure - University of AlabamaVirginia J. Howard - Univ Alabama Birmingham, Dept Epidemiol, Sch Publ Hlth, Birmingham, AL 35294 USAMary Cushman - University of VermontMartha K. Hovater - Univ Alabama Birmingham, Dept Biostat, Sch Publ Hlth, Birmingham, AL 35294 USAMonika M. Safford - Univ Alabama Birmingham, Dept Med, Div Prevent Med, Birmingham, AL 35294 USAGeorge Howard - Univ Alabama Birmingham, Dept Biostat, Sch Publ Hlth, Birmingham, AL 35294 USADavid C. Goff - Wake Forest Univ, Sch Med, Div Publ Hlth Sci, Winston Salem, NC 27109 USA
- Publication Details
- Neuroepidemiology, v 37(1), pp 39-44
- Publisher
- Karger
- Number of pages
- 6
- Grant note
- R01HL080477 / NATIONAL HEART, LUNG, AND BLOOD INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) U01 NS041588 / National Institute of Neurological Disorders and Stroke, National Institutes of Health, Department of Health and Human Services; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) National Institute of Neurological Disorders and Stroke, National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) U01NS041588 / NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000294217300006
- Scopus ID
- 2-s2.0-79961122495
- Other Identifier
- 991019231627204721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Public, Environmental & Occupational Health