Racial/ethnic and neighbourhood social vulnerability disparities in COVID-19 testing positivity, hospitalization, and in-hospital mortality in a large hospital system in Pennsylvania: A prospective study of electronic health records
Published, Version of Record (VoR)CC BY V4.0, Open
Abstract
COVID-19 Health disparities Neighborhoods Electronic Health Records
Disparities in COVID-19 mortality by race/ethnicity or neighborhood have been documented using surveillance data. We aimed to describe disparities by race/ethnicity and neighbourhood social vulnerability in COVID-19 positivity, hospitalization, and mortality.
We obtained data from the electronic health records of all individuals who tested positive for COVID-19 in the University of Pennsylvania Health System (UPHS) or were hospitalized with confirmed COVID-19 infection in five UPHS hospitals from March 1, 2020, to March 31, 2021. The main predictors were race/ethnicity and neighbourhood-level social vulnerability. The main outcomes were COVID-19 test positivity, hospitalization with COVID-19, and 30-day in-hospital mortality following hospitalization with COVID-19.
A total of 225,129 unique individuals received COVID-19 testing and 18,995 had a positive test result. A total of 5,794 unique patients were hospitalized with COVID-19 and 511 died in-hospital within 30 days. Racial/ethnic minority groups and residents of higher social vulnerability neighbourhoods had higher test positivity and risk of hospitalization. We did not see in-hospital mortality disparities during the first wave but observed 75% and 68% higher odds of death among Hispanic and Asians compared to Whites during subsequent waves.
We observed significant racial/ethnic and neighbourhood disparities in COVID-19 outcomes, especially test positivity and odds of hospitalization, highlighting the importance of equitably improving access to preventive measures to reduce SARS-CoV-2 infection, including reducing exposure to the virus and ensuring equity in vaccination.
National Institutes of Health.
Racial/ethnic and neighbourhood social vulnerability disparities in COVID-19 testing positivity, hospitalization, and in-hospital mortality in a large hospital system in Pennsylvania: A prospective study of electronic health records
Creators
Usama Bilal - Drexel University, Urban Health Collaborative
John B. Jemmott - Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania
Alina Schnake-Mahl - Drexel University, Urban Health Collaborative
Kathleen Murphy - Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania
Florence Momplaisir - Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania
Publication Details
The Lancet Regional Health - Americas, v 10, 100220
Publisher
Elsevier
Resource Type
Journal article
Language
English
Academic Unit
Urban Health Collaborative; Epidemiology and Biostatistics; Health Management and Policy
Web of Science ID
WOS:000904628000012
Scopus ID
2-s2.0-85126953453
Other Identifier
991019189129004721
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