Journal article
Radiation processed PAA composites for endosseous implants
Radiation physics and chemistry, v 9(4), pp 711-719
1977
Abstract
A new porous polymer-ceramic composite has been developed in this laboratory for use in bone restoration. The alumina-poly (acrylic acid) composite was developed by the polymerization of an aqueous acrylic acid solution in the presence of 0.3μ alumina powder. The polymerization was initiated by exposing the above mixture to gamma radiation at a dose rate of 0.24 Mrad/hr for a total dose of one Mrad. The radiation step was followed by a heat treatment step to drive the excess water out of the system and create the interconnecting porosity necessary for bone ingrowth. The porosity of the PAA-alumina composites was varied from 30–60 vol. % by adjusting the monomer concentration. Mechanical testing indicated ductile behavior with compressive yield strengths of 69 MPa and 125 MPa at 60 and 30 vol. % porosity respectively. The degree of cross-linking of the PAA matrix can be varied to induce different levels of water solubility thereby allowing the equilibrium water absorption to be easily controlled. When the polymer matrix was crosslinked to 60, 80 and 95%, composite swelling in water was 50, 25 and 15 vol. % respectively. Corresponding changes in mechanical properties as a function of crosslink density will also be presented. The ability to control the composite's properties allows a variety of implant applications such as endosseous root implants and ridge augmentation. Preliminary results for endosseous implants in dogs showed material biocompatibility and ease of body fluid diffusion. In addition, a distinct advantage of this material is its ease of fabrication and adaptation to various socket geometries. Implantation experiments are now in progress to determine the long term behavior of the material.
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Details
- Title
- Radiation processed PAA composites for endosseous implants
- Creators
- Ihab L. Kamel - Drexel University
- Publication Details
- Radiation physics and chemistry, v 9(4), pp 711-719
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:A1977DH62900028
- Scopus ID
- 2-s2.0-49349130027
- Other Identifier
- 991019174098904721