Journal article
Radiotherapy for Anal Cancer: Intensity-Modulated Radiotherapy and Future Directions
Surgical oncology clinics of North America, v 26(3), pp 467-475
Jul 2017
PMID: 28576183
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The treatment of anal cancer has evolved remarkably in the past 30 years. Definitive chemoradiotherapy is the standard of care, allowing organ preservation and maintenance of continence for most patients. This article reviews recent advances in radiotherapy planning and delivery that have resulted in improvements in treatment-related toxicity. Most notably, the advent and wide adoption of intensity-modulated radiotherapy provides a superior toxicity profile compared with older techniques, while maintaining similar oncologic outcomes. Current areas of active research include optimizing and individualizing treatment intensity and possible integration of biologic agents and immunotherapies in the treatment of anal cancer.
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Details
- Title
- Radiotherapy for Anal Cancer: Intensity-Modulated Radiotherapy and Future Directions
- Creators
- Serguei A Castaneda - Drexel UniversityLindsay B Romak - Christiana Care Health SystemVance G Nielsen
- Publication Details
- Surgical oncology clinics of North America, v 26(3), pp 467-475
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:000404421000011
- Scopus ID
- 2-s2.0-85019121940
- Other Identifier
- 991019357770104721
UN Sustainable Development Goals (SDGs)
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Oncology
- Surgery