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Rates of indoleamine synthesis in maturing mouse brain
Journal article

Rates of indoleamine synthesis in maturing mouse brain

Peter C. Baker, Kenneth M. Hoff and Cecilie A. Goodrich
General pharmacology, v 12(3), 151
1981
PMID: 7239146

Abstract

1. 1. Rates of 5-hydroxytryptamine (5-HT) synthesis in hemispheres and brainstem of maturing mouse brain have been made. Inhibitor methods with precursor assay have been employed. 2. 2. Rates of 5-HT synthesis are higher in neonatal brain than in vitro enzyme analysis might suggest. Changes in synthetic rate are more conservative in the hemispheres. The lowest synthetic rates are generally at 1 week of age. 3. 3. The possible general significance of maturational rate patterns for 5-HT synthesis are discussed.

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Pharmacology & Pharmacy
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