Journal article
Real-Time Salmonella Detection Using Lead Zirconate Titanate-Titanium Microcantilevers
MRS proceedings, v 845
2004
Abstract
Current methods for analysis of unknown powders in suspicious packages involve sending samples to laboratory facilities where a variety of time-consuming tests are performed. We have developed and investigated the use of a lead zirconate titanate - titanium (PZT-Ti) microcantilever for in situ detection of the common food- and water-born pathogen, Salmonella typhimurium. Using a bifunctional linking molecule to immobilize antibody on the titanium surface of the microcantilever, we can directly detect salmonella cells in suspensions of differing concentration. This novel surface functionalization technique along with the sub-nanogram sensitivity of the cantilever has allowed for direct quantification of S. typhimurium cells in suspension.
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Details
- Title
- Real-Time Salmonella Detection Using Lead Zirconate Titanate-Titanium Microcantilevers
- Creators
- John-Paul McGovern - Drexel UniversityWan Y. Shih - Drexel UniversityWei-Heng Shih - Drexel UniversityMauro Sergi - Drexel UniversityIrwin Chaiken - Drexel University
- Contributors
- C.T. Laurencin (Editor)E. Botchwey (Editor)
- Publication Details
- MRS proceedings, v 845
- Publisher
- Cambridge University Press
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Biochemistry and Molecular Biology; School of Biomedical Engineering, Science, and Health Systems; Materials Science and Engineering; Drexel University
- Other Identifier
- 991019520424804721