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Recognition and embolic potential of intraaortic atherosclerotic debris
Journal article   Open access   Peer reviewed

Recognition and embolic potential of intraaortic atherosclerotic debris

Dean G. Karalis, Krishnaswamy Chandrasekaran, Mark F. Victor, John J. Ross and Gary S. Mintz
Journal of the American College of Cardiology, v 17(1), pp 73-78
Jan 1991
DOI: https://doi.org/10.1016/0735-1097(91)90706-F
PMID: 1987243
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1016/0735-1097(91)90706-fView
Published, Version of Record (VoR) Open

Abstract

Atherosclerotic disease of the thoracic aorta is common in the elderly and patients with clinical coronary artery disease. Although emholization can occur from atherosclerotic debris within the thoracic aorta, it is not commonly considered in the differential diagnosis of the source of a systemic embolism. In the current study, the prevalence, clinical significance and embolic potential of intraaortic atherosclerotic debris as detected by transesophageal echocardiography was determined. Intraaortic atherosclerotic debris was identified in 38 17%) of 556 patients undergoing transesophageal echocardiography. An embolic event occurred among 11 (31%) of the 36 study patients with inlraaortic atherosclerotic debris. The incidence of an embolic event was higher when the debris was pedunculated and highly mobile (8 [73%] of 11 patients) than when it was layered and immobile (3 [12%] of 25 patients) (p < 0.002). Among 15 patients undergoing an invasive procedure of the aorta, the incidence of embolism was 27%. In conclusion, in a patient with an embolic event, the thoracic aorta should be considered as a potential source. Transesophageal echocardiography can reliably detect intraaortic atherosclerotic debris, and when it is identified, an invasive aortic procedure should be avoided if possible.

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Web of Science research areas
Cardiac & Cardiovascular Systems
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