Journal article
Recurrence of Posterior Uveal Melanoma after 60Co Episcleral Plaque Therapy
Ophthalmology (Rochester, Minn.), v 96(3), pp 382-388
Mar 1989
PMID: 2710530
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Abstract
The authors analyzed the clinical and follow-up data on 277 selected patients with primary choroidal or ciliochoroidal melanoma who were treated with 60Co plaque radiotherapy between 1976 and 1982. Local recurrence of the irradiated melanoma developed in 39 (14%) patients during the follow-up interval. The 5-year tumor recurrence rate (Kaplan-Meier) was estimated to be 12%. Multivariate prognostic factor analysis (Cox proportional hazards modeling) identified the largest linear tumor dimension and proximity of the posterior margin of the tumor to the optic nerve head as predictors of recurrence. The 5-year survival rate of patients whose tumors recurred (58%) was significantly (logrank test P = 0.0023) worse than that of patients whose tumor remained clinically controlled (82%).
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Details
- Title
- Recurrence of Posterior Uveal Melanoma after 60Co Episcleral Plaque Therapy
- Creators
- Ulf L. Karlsson - Division of Radiation Oncology, the Department of Radiation Oncology and Nuclear Medicine, Hahnemann University School of Medicine, PhiladelphiaJames J. Augsburger - Wills Eye HospitalJerry A. Shields - Wills Eye HospitalArnold M. Markoe - Division of Radiation Oncology, the Department of Radiation Oncology and Nuclear Medicine, Hahnemann University School of Medicine, PhiladelphiaLuther W. Brady - Division of Radiation Oncology, the Department of Radiation Oncology and Nuclear Medicine, Hahnemann University School of Medicine, PhiladelphiaReginald Woodleigh - Radiation Safety, the Department of Radiation Oncology and Nuclear Medicine, Hahnemann University School of Medicine, Philadelphia
- Publication Details
- Ophthalmology (Rochester, Minn.), v 96(3), pp 382-388
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:A1989T559400023
- Scopus ID
- 2-s2.0-0024556584
- Other Identifier
- 991019183929904721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Ophthalmology