Journal article
Reduction of low-density lipoprotein cholesterol, plasma viscosity, and whole blood viscosity by the application of pulsed corona discharges and filtration
Review of scientific instruments, v 84(3), pp 034301-034301
01 Mar 2013
PMID: 23556829
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The present study investigated the feasibility of applying pulsed corona discharges to blood plasma to reduce the viscosity of blood plasma and whole blood. Blood plasma was separated from blood cells, treated with corona discharges, and filtered before it was re-mixed with blood cells. Plasma viscosity (PV), whole blood viscosity (WBV), and low-density lipoprotein (LDL)-c concentration were measured before and after the corona treatment and filtration. Both PV and WBV increased in the case of the corona treatment only, whereas both of them decreased in the case of the corona treatment plus filtration. In particular, the LDL-c decreased in the case of the corona treatment plus filtration by 31.5% from the baseline value. The effect of the corona treatment on the reduction of the WBV was significant at low shear rates, but not at high shear rates, suggesting that the precipitation of the molecules in blood plasma by the corona treatment and subsequent removal may suppress the aggregation of erythrocytes and improve rheological properties of blood. (C) 2013 American Institute of Physics. [http://dx.doi.org/10.1063/1.4797478]
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Details
- Title
- Reduction of low-density lipoprotein cholesterol, plasma viscosity, and whole blood viscosity by the application of pulsed corona discharges and filtration
- Creators
- Jin M. Jung - Drexel UniversityAlexander Fridman - Drexel UniversityDaniel J. Cho - Rheovector LLC, Camden, NJ 08103 USAYoung I. Cho - Drexel University
- Publication Details
- Review of scientific instruments, v 84(3), pp 034301-034301
- Publisher
- American Institute of Physics
- Number of pages
- 6
- Grant note
- FA9550-11-028-DEF / Air Force Office of Scientific Research (AFOSR); United States Department of Defense
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000316966200029
- Scopus ID
- 2-s2.0-84875784680
- Other Identifier
- 991019168824004721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Instruments & Instrumentation
- Physics, Applied