Journal article
Regression of Retinoblastoma After Plaque Radiotherapy
American journal of ophthalmology, v 115(2), pp 181-187
Feb 1993
PMID: 8430727
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
A review of 400 consecutive patients with retinoblastoma disclosed that 103 tumors in 103 eyes were treated with solitary plaque radiotherapy. The tumors were from 1 to 16 mm (mean, 7 mm) in basal diameter and from 1 to 8 mm (mean, 4 mm) in thickness. Thirty-one tumors were treated with plaque radiotherapy as initial treatment, whereas 72 tumors were treated with plaque radiotherapy as secondary treatment after failure of other methods. Of the 102 tumors on which adequate follow-up data were available, all responded initially to plaque radiotherapy with tumor regression. Over the mean follow-up of 38 months (range, six to 192 months), 89 tumors (87%) showed persistent regression and 13 (13%) showed tumor recurrence. The recurrence occurred at a mean interval of five months (range, one to 11 months) after plaque radiotherapy. A statistical analysis of tumor size, tumor location, tumor proximity to the optic disk and foveola, presence of vitreous seeds, radioactive plaque diameter, plaque shape, radioisotope, and primary or secondary treatment disclosed no important predictors of tumor recurrence. Carefully selected retinoblastoma, even juxtapapillary and macular tumors and those with localized vitreous seeds, can be successfully treated with plaque radiotherapy.
Metrics
Details
- Title
- Regression of Retinoblastoma After Plaque Radiotherapy
- Creators
- Carol L. Shields - Wills Eye HospitalJerry A. Shields - Wills Eye HospitalSilvana Minelli - Wills Eye HospitalPatrick De Potter - Wills Eye HospitalCarlos Hernandez - Hahnemann University HospitalJacqueline Cater - Thomas Jefferson UniversityLuther Brady - Hahnemann University Hospital
- Publication Details
- American journal of ophthalmology, v 115(2), pp 181-187
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:A1993KK88700007
- Scopus ID
- 2-s2.0-0027447969
- Other Identifier
- 991019184199104721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Ophthalmology