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Journal article
Regulation of Sleep and Growth Hormone in Adolescent Depression
Journal of the American Academy of Child and Adolescent Psychiatry, v 31(4), pp 615-621
1992
PMID: 1644723
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Abstract
This article reviews findings of sleep, growth hormone (GH), and cortisol measures from a number of separate controlled studies of prepubertal and adolescent depression carried out by Puig-Antich and colleagues since 1978. New data are presented comparing 24-hour GH measures in adolescents with major depressive disorder (MDD) (
N = 44; mean age = 14.8 ± 2.0) to normal control adolescents (
N = 37; mean age = 15.3 ± 1.5). There were no significant overall group differences in summary GH measures between MDD and normal controls Splitting the MDD group on the basis of suicidality (definite plan or attempt) (
N = 20), revealed a significant blunting of sleep GH compared to the nonsuicidal group (
N = 24). These results are discussed in the context of the other sleep and neuroendocrine findings in this population, with evidence for dysregulation around sleep onset. The influences of development on sleep and GH regulation are also considered.
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Details
- Title
- Regulation of Sleep and Growth Hormone in Adolescent Depression
- Creators
- RONALD E. Dahl - University of PittsburghNEAL D. Ryan - Columbia UniversityDOUGLAS E. Williamson - Columbia UniversityPAUL J. Ambrosini - Columbia UniversityHARRIS Rabinovich - Columbia UniversityHANA Novacenko - Columbia UniversityBEVERLY Nelson - Columbia UniversityJOAQUIM PUIG-ANTICH - Columbia University
- Publication Details
- Journal of the American Academy of Child and Adolescent Psychiatry, v 31(4), pp 615-621
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:A1992JD37700007
- Scopus ID
- 2-s2.0-0026717047
- Other Identifier
- 991019184024304721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Pediatrics
- Psychiatry
- Psychology, Developmental