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Relation between Very Low Birth Weight and Developmental Delay among Preschool Children Without Disabilities
Journal article   Open access   Peer reviewed

Relation between Very Low Birth Weight and Developmental Delay among Preschool Children Without Disabilities

Diana E. Schendel, Joseph W. Stockbauer, Howard J. Hoffman, Allen A. Herman, Cynthia J. Berg and Wayne F. Schramm
American journal of epidemiology, v 146(9), pp 740-749
01 Nov 1997
PMID: 9366622
url
https://doi.org/10.1093/oxfordjournals.aje.a009350View
Published, Version of Record (VoR) Open

Abstract

birth weight child development infant very low birth weight
The authors examined the relation between very low birth weight (VLBW: <1,500 g) and possible developmental delay (DELAY) in the absence of frank developmental disability among young children. The prevalence of DELAY in a population-based cohort (Missouri resident births born from December 1989 through March 1991) of singleton VLBW children (n = 367) was compared with the prevalence of DELAY among both moderately low birth weight (MLBW: 1,500–2,499 g; n = 553) and normal birth weight (NBW: ≥2,500 g; n = 555) singleton control children. DELAY was defined by nine measures of performance on the Denver Developmental Screening Test II at a median adjusted age of 15 months (range: 9–34 months). Subjects were asymptomatic for disabling conditions at developmental follow-up. Apparently well VLBW children were consistently at greater risk for both moderate and severe measures of DELAY and for DELAY across four functional areas than were either the MLBW (adjusted odds ratios: 1.4–2.7) or NBW children (adjusted odds ratios: 2.1–6.3). The greatest prevalence of DELAY tended to be among appropriate-for-gestational age VLBW children who were also the most premature. This study supports developmental follow-up of nondisabled VLBW children because of the significantly elevated risk for DELAY among apparently normal infants.

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