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Relationship among different skin dose definitions in high-dose-rate (HDR) balloon breast brachytherapy
Journal article   Open access   Peer reviewed

Relationship among different skin dose definitions in high-dose-rate (HDR) balloon breast brachytherapy

Yongbok Kim, James D. Christensen, Shaakir Hasan and Mark G. Trombetta
Journal of radiation oncology, v 7(4), pp 335-343
01 Dec 2018
DOI: https://doi.org/10.1007/s13566-018-0364-5
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1007/s13566-018-0364-5View
Published, Version of Record (VoR)Maybe Open Access (Publisher Bronze),  Open

Abstract

Life Sciences & Biomedicine Oncology Science & Technology
ObjectiveTo establish the relationship among various skin dosimetric indices and different volumetric definitions of skin in high-dose-rate (HDR) balloon breast brachytherapy.MethodsFifty breast cancer patients were treated with HDR balloon brachytherapy. The MammoSite (R) applicator was used for 40 patients and the Contura (R) applicator for 10 patients. Skin structure was retrospectively defined by expanding the skin surface internal to the body with a thickness of 1, 2, 3, 4, or 5mm in one method. In another method, the skin was defined by expanding its external to the body to demonstrate the maximum point dose on the skin surface. For each skin structure defined by six different methods, three dosimetric data points extracted from dose-volume histograms were compared. Dmax was defined as the maximum point dose, and D1cc and D0.1cc were defined as the minimum dose to 1 cm(3) and 0.1 cm(3) of the most irradiated skin volume, respectively. The relationship among 18 dosimetric parameters was presented in graphs, and linear curve fitting was performed to provide mathematical formulas.ResultsFor each skin definition, the Dmax, D1cc, and D0.1cc values show a linear relationship such that Dmax is the largest, D0.1cc is the next, and D1cc is the smallest value. For each dosimetric parameter, there was a linear relationship among the dosimetric indices for 6 different skin definitions. For clinical use, all linear relationships were displayed in graphs and two parameters for linear fitting were provided. Average R-2 value for curve fitting was 0.978.ConclusionThe presented relationships can be developed in each individual institution and convert one dosimetric index to another for different skin definitions.

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Collaboration types
Domestic collaboration
Web of Science research areas
Oncology
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