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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Relationships among Clinical Factors and Patient-reported Outcome Measures in Adults with Convergence Insufficiency
Optometry and vision science, v 99(9), pp 692-701
01 Sep 2022
PMID: 35914096
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
SIGNIFICANCE: When exploring relationships among clinical measures and patient-reported outcome measures in adults with convergence insufficiency, worse symptoms (Convergence Insufficiency Symptom Survey [CISS] score) seemed to be correlated with worse reading function domain score (Adult Strabismus-20 quality-of-life questionnaire). After treatment, improved symptoms were associated with improved reading function quality of life.
PURPOSE: This study aimed to explore relationships between clinical measures and patient-reported outcome measures in adults undergoing treatment for symptomatic convergence insufficiency.
METHODS: In a prospective multicenter observational study, we evaluated adults with symptomatic convergence insufficiency (i.e., clinical measures of near exodeviation, receded near point of convergence, reduced near positive fusional vergence; CISS score >= 21). Fifty-seven participants treated with vision therapy/exercises (n = 35) or base-in prism (n = 22) were analyzed. Spearman correlation coefficients (R) were used to assess associations among the three clinical measures and patient-reported outcome measures (CISS, Diplopia Questionnaire, four Adult Strabismus-20 quality-of-life domains) before treatment (baseline) and after 10 weeks and 1 year. Associations were interpreted to be present when the lower limit of the 95% confidence interval (CI) was moderate to strong (R >= 0.4).
RESULTS: Amongmultiple exploratory analyses, the onlymoderate to strong baseline correlation was between worse CISS and worse Adult Strabismus-20 reading function scores (R = 0.62; 95% CI, 0.43 to 0.76). Regarding change in measures with treatment, the only moderate to strong correlations were between improved CISS and improved Adult Strabismus-20 reading function scores for prism at 10 weeks (R = 0.78; 95% CI, 0.52 to 0.91) and 1 year (R = 0.85; 95% CI, 0.65 to 0.94) and for vision therapy/exercises at 1 year (R = 0.78; 95% CI, 0.57 to 0.89).
CONCLUSIONS: In exploratory analyses, we found positive correlations between CISS symptom scores and reading function quality-of-life scores. The absence of correlations between symptoms and individual clinical measures is consistent with clinical experience that, in convergence insufficiency, symptoms and clinical findings can be discordant.
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Details
- Title
- Relationships among Clinical Factors and Patient-reported Outcome Measures in Adults with Convergence Insufficiency
- Creators
- Ingryd J. Lorenzana - Adv Vis Ctr, Schaumburg, IL 60194 USADavid A. Leske - Mayo ClinicSarah R. Hatt - Mayo ClinicTrevano W. Dean - Jaeb Center for Health ResearchErin C. Jenewein - Salus UniversityLinda R. Dagi - Boston Children's MuseumCasey J. Beal - University of FloridaYi Pang - Ticho Eye Associates, Chicago Ridge, IL USADashaini Retnasothie - Marshall B. Ketchum UniversityChristina A. Esposito - Midwestern UniversityS. A. Erzurum - Eye Care AssociatesAmy E. Aldrich - Snowy Range Vis Ctr, Laramie, WY USAEric R. Crouch - Virginia Eye ConsultantsZhuokai Li - Jaeb Center for Health ResearchRaymond T. Kraker - Jaeb Center for Health ResearchJonathan M. Holmes - University of ArizonaSusan A. Cotter - Marshall B. Ketchum UniversityPediat Eye Dis Investigator Grp
- Publication Details
- Optometry and vision science, v 99(9), pp 692-701
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 10
- Grant note
- EY023198; EY011751; EY024333; EY018810 / National Eye Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pennsylvania College of Optometry (PCO)
- Web of Science ID
- WOS:000851158500004
- Scopus ID
- 2-s2.0-85138125765
- Other Identifier
- 991022004946504721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Ophthalmology