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Relative entropy as a universal metric for multiscale errors
Journal article   Peer reviewed

Relative entropy as a universal metric for multiscale errors

Aviel Chaimovich and M Scott Shell
Physical review. E, Statistical, nonlinear, and soft matter physics, v 81(6 Pt 1), 060104
Jun 2010
PMID: 20866366

Abstract

We show that the relative entropy, Srel, suggests a fundamental indicator of the success of multiscale studies, in which coarse-grained (CG) models are linked to first-principles (FP) ones. We demonstrate that Srel inherently measures fluctuations in the differences between CG and FP potential energy landscapes, and develop a theory that tightly and generally links it to errors associated with coarse graining. We consider two simple case studies substantiating these results, and suggest that Srel has important ramifications for evaluating and designing coarse-grained models.

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Web of Science research areas
Physics, Fluids & Plasmas
Physics, Mathematical
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