Journal article
Relaxation of muscle fibres by photolysis of caged ATP
Nature (London), v 300(5894), pp 701-705
23 Dec 1982
PMID: 7177194
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
A novel method has been developed for studying the reaction kinetics of the force-generating mechanism in muscle. Inert photolabile precursors of ATP or ADP are incorporated into muscle fibres having their surface membrane barrier removed. The nucleotide is then rapidly liberated by laser pulse photolysis. This circumvents the limitation in time resolution set by diffusion of nucleotide from the medium bathing the fibre. This laser photolysis method may be applicable to studies of the dynamic properties of many biological systems.
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Details
- Title
- Relaxation of muscle fibres by photolysis of caged ATP
- Creators
- Y E Goldman - University of PennsylvaniaM G Hibberd - University of PennsylvaniaJ A McCray - Drexel UniversityD R Trentham - University of Pennsylvania
- Publication Details
- Nature (London), v 300(5894), pp 701-705
- Publisher
- Springer Nature
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:A1982PU97700040
- Scopus ID
- 2-s2.0-0020438546
- Other Identifier
- 991019173898204721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Biochemistry & Molecular Biology