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Report of a National conference on Liver Allocation in Patients with Hepatocellular Carcinoma in the United States
Journal article   Open access   Peer reviewed

Report of a National conference on Liver Allocation in Patients with Hepatocellular Carcinoma in the United States

Elizabeth A. Pomfret, Kenneth Washburn, Christoph Wald, Michael A. Nalesnik, David Douglas, Mark Russo, John Roberts, David J. Reich, Myron E. Schwartz, Luis Mieles, …
Liver transplantation, v 16(3), pp 262-278
01 Mar 2010
PMID: 20209641
url
https://doi.org/10.1002/lt.21999View
Published, Version of Record (VoR)CC BY V4.0 Open

Abstract

Gastroenterology & Hepatology Life Sciences & Biomedicine Science & Technology Surgery Transplantation
A national conference was held to better characterize the long-term outcomes of liver transplantation (LT) for patients with hepatocellular carcinoma (HCC) and to assess whether it is justified to continue the policy of assigning increased priority for candidates with early-stage HCC on the transplant waiting list in the United States The objectives of the conference were to address specific HCC issues as they relate to liver allocation, develop a standardized pathology report form for the assessment of the explanted liver, develop more specific imaging criteria for HCC designed to qualify LT candidates for automatic Model for End-Stage Liver Disease (MELD) exception points without the need for biopsy, and develop a standardized pretransplant imaging report form for the assessment of patients with liver lesions At the completion of the meeting, there was agreement that the allocation policy should result in similar risks of removal from the waiting list and similar transplant rates for HCC and non-HCC candidates In addition, the allocation policy should select HCC candidates so that there are similar posttransplant outcomes for HCC and non-HCC recipients There was a general consensus for the development of a calculated continuous HCC priority score for ranking HCC candidates on the list that would incorporate the calculated MELD score, alpha-fetoprotein, tumor size, and rate of tumor growth Only candidates with at least stage T2 tumors would receive additional HCC priority points Liver Transpl 16:262-278, 2010. (C) 2009 AASLD.

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Collaboration types
Domestic collaboration
Web of Science research areas
Gastroenterology & Hepatology
Surgery
Transplantation
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