Journal article
Residential exposure to traffic-related air pollution and survival after heart failure
Environmental health perspectives, v 116(4), pp 481-485
01 Apr 2008
PMID: 18414630
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Although patients with heart failure (HF) have been identified as particularly susceptible to the acute effects of air pollution, the effects of long-term exposure to air pollution on patients with this increasingly prevalent disease are largely unknown.
This study was designed to examine the mortality risk associated with residential exposure to traffic-related air pollution among HF patients.
A total of 1,389 patients hospitalized with acute HF in greater Worcester, Massachusetts, during 2000 were followed for survival through December 2005. We used daily traffic within 100 and 300 m of residence as well as the distance from residence to major roadways and to bus routes as proxies for residential exposure to traffic-related air pollution. We assessed mortality risks for each exposure variable using Cox proportional hazards models adjusted for prognostic factors.
After the 5-year follow-up, only 334 (24%) subjects were still alive. An interquartile range increase in daily traffic within 100 m of home was associated with a mortality hazard ratio (HR) of 1.15 [95% confidence interval (CI), 1.05-1.25], whereas for traffic within 300 m this association was 1.09 (95% CI, 1.01-1.19). The mortality risk decreased with increasing distance to bus routes (HR = 0.88; 95% CI, 0.81-0.96) and was larger for those living within 100 m of a major roadway or 50 m of a bus route (HR = 1.30; 95% CI, 1.13-1.49). Adjustment for area-based income and educational level slightly attenuated these associations.
Residential exposure to traffic-related air pollution increases the mortality risk after hospitalization with acute HF. Reducing exposure to traffic-related emissions may improve the long-term prognosis of HF patients.
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Details
- Title
- Residential exposure to traffic-related air pollution and survival after heart failure
- Creators
- Mercedes Medina-Ramón - Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA. mmedina@imim.esRobert Goldberg - Brown UniversitySteven MellyMurray A Mittleman - Beth Israel Deaconess Medical CenterJoel Schwartz - Harvard University
- Publication Details
- Environmental health perspectives, v 116(4), pp 481-485
- Grant note
- R37 HL69874 / NHLBI NIH HHS ES011636 / NIEHS NIH HHS R01 ES011636 / NIEHS NIH HHS R37 HL069874 / NHLBI NIH HHS ES000002 / NIEHS NIH HHS P30 ES000002 / NIEHS NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative
- Web of Science ID
- WOS:000254566500029
- Scopus ID
- 2-s2.0-45749139624
- Other Identifier
- 991021875476304721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Environmental Sciences
- Public, Environmental & Occupational Health
- Toxicology