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Respiratory Complications in Infants with Retinopathy of Prematurity (ROP) Requiring Laser Photocoagulation
Journal article   Peer reviewed

Respiratory Complications in Infants with Retinopathy of Prematurity (ROP) Requiring Laser Photocoagulation

Novisi Arthur, Emma Byrne, Folasade Kehinde, Vineet Bhandari and Vilmaris Quinones Cardona
American journal of perinatology
10 Dec 2021
DOI: https://doi.org/10.1055/s-0041-1740347
PMID: 34891193
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

Life Sciences & Biomedicine Obstetrics & Gynecology Pediatrics Science & Technology
Objective The objective of this paper was to describe peri-procedural events and complications of infants requiring laser photocoagulation for retinopathy of prematurity (ROP) in a level IV neonatal intensive care unit. Study Design A retrospective chart review was performed of neonates requiring ROP exams from January 2017 to August 2020. Baseline maternal and neonatal characteristics, ROP exam findings, and associated treatment were analyzed. Group characteristics were compared based on the need for laser photocoagulation. Subgroup analysis of the laser group including respiratory outcomes, cardiorespiratory index (CRI) scores, and pain scores was also performed. Results Neonatal and maternal characteristics in the laser ( n = 27) and non-laser ( n = 172) groups were assessed. Of the 81.5% (22/27) that required re-intubation for laser, 36% (8/22) had >1 intubation and 18% (4/22) had >1 extubation attempt. The average duration of intubation following laser was 2.46 +/- 7.13 days, with 40% (9/22) needing peri-extubation steroids and 18% (4/22) racemic epinephrine to facilitate extubation. Mean total respiratory support time post-laser was 8.65 +/- 15.23 days. Mean neonatal pain, agitation, and sedation scores after laser were zero immediately after the procedure, 0.09 +/- 0.33 at 12 hours, 0.11 +/- 0.47 at 24 hours, and 0.11 +/- 0.51 at 48 hours. The mean CRI scores were 1 +/- 0 immediately after the procedure, 1.17 +/- 0.4 at 12 hours, 1.41 +/- 0.20 at 24 hours, and 1 +/- 0 at 48 hours. Conclusion Nearly all infants undergoing laser photocoagulation for ROP in our cohort required intubation and continued respiratory support. Despite stability during the procedure, complications from intubation were common.

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2 citations in Web of Science
2 citations in Scopus

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#3 Good Health and Well-Being

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Web of Science research areas
Obstetrics & Gynecology
Pediatrics
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