Journal article
Respiratory syncytial virus immune globulin intravenous: Indications for use
Pediatrics (Evanston), v 99(4), pp 645-650
01 Apr 1997
PMID: 9093323
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Respiratory syncytial virus immune globulin intravenous (RSV-IGIV) has been approved by the Food and Drug Administration for use in the prevention of severe RSV infections in infants and children younger than 24 months with bronchopulmonary dysplasia or a history of premature birth (less than or equal to 35 weeks of gestation). RSV-IGIV administered monthly during the RSV season resulted in a 41% to 65% reduction in hospitalization rates in two clinical trials; however, RSV-IGIV is costly, and intravenous administration can be logistically demanding. RSV-IGIV should be considered for infants with bronchopulmonary dysplasia who are receiving or have received oxygen therapy in the past 6 months. Infants with gestational ages of 32 weeks or less may also benefit clinically from RSV-IGIV prophylaxis. Immunization with measles-containing vaccines should be delayed for 9 months after the last dose of RSV-IGIV, but no changes need to be made for all other routinely administered vaccines. RSV-IGIV has not been approved for use in children with congenital heart disease, and available data indicate that RSV-IGIV should not be administered to children with cyanotic congenital heart disease because of safety concerns.
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Details
- Title
- Respiratory syncytial virus immune globulin intravenous: Indications for use
- Creators
- N A HalseyJ S AbramsonP J ChesneyM C FisherM A GerberD S GromischS KohlS M MarcyD L MurrayG D OverturfR J WhitleyR YogevC B HallJ C OverallR BerkelmanW A OrensteinR BreimanM C HardegreeR F JacobsN E MacDonaldN R RabinovitchW OhL R BlackmonA A FanaroffB V KirkpatrickH M MacDonaldC A MillerL A PapileC T ShoemakerM E SpeerP JohnsonM F GreeneD D McMillanD RowleyL L WrightJ C LangerCommittee on Infectious Diseases Committee on Fetus and Newborn
- Publication Details
- Pediatrics (Evanston), v 99(4), pp 645-650
- Publisher
- Amer Acad Pediatrics
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:A1997WQ80200047
- Scopus ID
- 2-s2.0-11444266213
- Other Identifier
- 991021930897404721
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- Web of Science research areas
- Pediatrics