Journal article
Retention and Acquisition of Classical Trace Conditioned Responses by Rabbits With Hippocampal Lesions
Behavioral neuroscience, v 100(5), pp 745-752
Oct 1986
PMID: 3778637
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The effects of dorsal hippocampal lesions on retention of classical trace conditioned responses were examined using the rabbit nictitating membrane preparation. Animals were trained to criteria and then lesioned either in the cortex or in the hippocampus and the cortex. Hippocampal damage had no effect on the retention of responses but produced significantly longer onset latencies. A control group of hippocampal animals acquired conditioned responses (CRs) at least as quickly as the prelesion subjects, and they also exhibited longer response onset latency. A second experiment evaluated the performance of hippocampal lesioned animals in classical trace conditioning with either a low-intensity periorbital shock or corneal air puff as the unconditioned stimulus (UCS). Hippocampal animals successfully acquired CRs under both conditions but exhibited an alteration of response onset which was dependent on the form of the UCS. Hippocampal animals displayed shorter response onset in the air-puff condition and longer response onset in the shock condition. Cortical animals timed responses consistently regardless of the UCS. These findings strongly suggest that the hippocampus modulates temporal characteristics of learned behavior.
Metrics
Details
- Title
- Retention and Acquisition of Classical Trace Conditioned Responses by Rabbits With Hippocampal Lesions
- Creators
- Richard L Port - Ohio UniversityAnthony G Romano - Ohio UniversityJoseph E Steinmetz - Ohio UniversityAdel A Mikhail - Department of Zoology, Ohio UniversityMichael M Patterson - College of Osteopathic Medicine, Ohio University
- Publication Details
- Behavioral neuroscience, v 100(5), pp 745-752
- Publisher
- American Psychological Association
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- MD (Doctor of Medicine) Program
- Web of Science ID
- WOS:A1986E430700016
- Scopus ID
- 2-s2.0-0023025463
- Other Identifier
- 991014877696704721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Behavioral Sciences
- Neurosciences