Journal article
Retention in HIV Care Among HIV-Seropositive Pregnant and Postpartum Women in Uganda: Results of a Randomized Controlled Trial
AIDS and behavior, v 24(11), pp 3164-3175
01 Nov 2020
PMID: 32314120
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We tested an intervention that aimed to increase retention in antiretroviral therapy (ART) among HIV-positive pregnant and postpartum women, a population shown to be vulnerable to poor ART outcomes. 133 pregnant women initiating ART at 2 hospitals in Uganda used real time-enabled wireless pill monitors (WPM) for 1 month, and were then randomized to receive text message reminders (triggered by late dose-taking) and data-informed counseling through 3 months postpartum or standard care. We assessed "full retention" (proportion attending all monthly clinic visits and delivering at a study facility; "visit retention" (proportion of clinic visits attended); and "postpartum retention" (proportion retained at 3 months postpartum). Intention-to-treat and per protocol analyses found that retention was relatively low and similar between groups, with no significant differences. Retention declined significantly post-delivery. The intervention was unsuccessful in this population, which experiences suboptimal ART retention and is in urgent need of effective interventions.
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Details
- Title
- Retention in HIV Care Among HIV-Seropositive Pregnant and Postpartum Women in Uganda: Results of a Randomized Controlled Trial
- Creators
- Lora L Sabin - Boston UniversityNafisa Halim - Boston UniversityDavidson H Hamer - Boston UniversityElizabeth M Simmons - Boston UniversitySivani Jonnalagadda - Boston UniversityAnna Larson Williams - Boston UniversityHarriet Chemusto - Mildmay UgandaAllen L Gifford - Boston UniversityRachael Bonawitz - Boston UniversityPhilip Aroda - Mildmay UgandaMary DeSilva - New England CollegeJulia Gasuza - Mildmay UgandaBarbara Mukasa - Mildmay UgandaLisa J Messersmith - Boston University
- Publication Details
- AIDS and behavior, v 24(11), pp 3164-3175
- Publisher
- Springer Nature
- Grant note
- 1R34MN103075 / NIMH NIH HHS R34 DA032423 / NIDA NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:000527482900001
- Scopus ID
- 2-s2.0-85084063154
- Other Identifier
- 991021448055004721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health
- Social Sciences, Biomedical