Journal article
Retrolental Fibroplasia and Blood Transfusion in Very Low-Birth-Weight Infants
Pediatrics (Evanston), v 68(6), pp 770-774
Dec 1981
PMID: 6895663
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The relative contribution of transfusions of adult blood to the development of retrolental fibroplasia (RLF) in very low-birth-weight infants was examined. Five years of experience with the expanded use of replacement and exchange transfusions in 90 infants with birth weight ≤1,250 gm was reviewed. Twenty percent of the infants developed cicatricial RLF. Exchange transfusion was not related to development of cicatricial RLF. The incidence of RLF in infants receiving ≥130 ml of packed red blood cells per kilogram of birth weight as replacement blood transfusion (RBT) was significantly higher (42.9%) than that in infants receiving 61 to 131 ml of packed red blood cells per kilogram (15.4%) and infants receiving ≤60 ml of packed red blood cells per kilogram (0%), P < .001. The need for RBT, however, was strongly correlated (r = .85, P < .001) with increasing duration of O2 therapy. When O2 therapy was controlled for, the association between RBT and RLF did not achieve statistical significance (P = .07). The association between RBT and RLF remained significant when adjusted for duration of therapy in fractional inspired oxygen (FIO2) >0.4. Further detailed studies of large numbers of susceptible infants are warranted to assess the magnitude of the contribution of transfusions of adult blood to development of RLF.
Metrics
3 Record Views
Details
- Title
- Retrolental Fibroplasia and Blood Transfusion in Very Low-Birth-Weight Infants
- Creators
- Linda M. Sacks - University of PennsylvaniaDavid B. Schaffer - University of PennsylvaniaEndla K. Anday - University of PennsylvaniaGeorge J. Peckham - University of PennsylvaniaMaria Delivoria-Papadopoulos - University of Pennsylvania
- Publication Details
- Pediatrics (Evanston), v 68(6), pp 770-774
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:A1981MS99500003
- Scopus ID
- 2-s2.0-0019817724
- Other Identifier
- 991021463691304721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Pediatrics