Journal article
Retrospective Analysis of Bleeding and Wound Complications After Preoperative Administration of Ketorolac in Acute Appendicitis
Transformative Medicine, v 4(2), pp 14-18
30 Jun 2025
Abstract
Introduction: Opioids are a mainstay of acute pain management and provide excellent analgesia for severe pain. However, their side effect profile and complication rates raise concerns regarding routine administration. Methods: This study is a retrospective cohort study of 1415 patients in a single tertiary care center comparing bleeding and operative complications in patients administered ketorolac prior to appendectomy. Results: There was no difference between the ketorolac and non-ketorolac groups regarding blood loss (0.7% vs 0.6%, p=0.572) and hemoperitoneum (0.4% vs 0.6%, p = 0.43) There was no difference between the groups regarding need for re-exploration (0.6% vs 0.6%, p=0.643). Discussion: The use of the cyclooxygenase inhibitor, ketorolac, did not result in an increase of surgical complications in patients undergoing appendectomy.
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Details
- Title
- Retrospective Analysis of Bleeding and Wound Complications After Preoperative Administration of Ketorolac in Acute Appendicitis
- Creators
- Kate YurickJahan AslamiJohn LeMoineLuke RovenstineTan TranTraci DeanerThomas WasserAdam Sigal
- Publication Details
- Transformative Medicine, v 4(2), pp 14-18
- Number of pages
- 5
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Emergency Medicine
- Other Identifier
- 991022161531604721