Journal article
Richter's syndrome associated with loss of response to transforming growth factor-beta
Leukemia research, v 18(2), pp 85-89
1994
PMID: 8107492
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
A patient with chronic lymphocytic leukemia developed a large cell lymphoma apparently derived from the same neoplastic B-cell clone (Richter's syndrome). At the same time, mitogen-stimulated proliferation of the patient's circulating leukemic B-cells was no longer inhibited by the regulatory cytokine transforming growth factor-beta (TGF-β), suggesting that such loss of inhibition might be contributing to the clinical and biological progression of the disease.
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Details
- Title
- Richter's syndrome associated with loss of response to transforming growth factor-beta
- Creators
- Peter C. Nowell - University of PennsylvaniaJonni S. Moore - University of PennsylvaniaFloyd E. Fox - University of PennsylvaniaRenold J. Capocasale - University of PennsylvaniaJeffrey A. Kant - University of PennsylvaniaEmmanuel C. Besa - Drexel University
- Publication Details
- Leukemia research, v 18(2), pp 85-89
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Microbiology and Immunology
- Web of Science ID
- WOS:A1994MW66800003
- Scopus ID
- 2-s2.0-0028096136
- Other Identifier
- 991019183964704721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Hematology
- Oncology