Objective
To evaluate the role of gynecologic findings in Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) by reviewing current international guidelines and identifying relevant gynecologic co‐morbidities.
Methods
This consensus statement was developed through a systematic four‐phase process: (1) comprehensive literature review across PubMed/MEDLINE, Embase, Cochrane Library, and Web of Science databases (inception‐January 2025) using predefined search terms related to IC/BPS and gynecologic conditions; (2) assembly of a 6‐member multidisciplinary expert panel including urologists, urogynecologists, gynecologists and pain specialists; (3) consensus development via modified Delphi technique comprising several electronic rating rounds and a face‐to‐face meeting, with consensus defined as ≥ 80% agreement; and (4) manuscript preparation with iterative review.
Results
A number of associated gynecologic disorders may overlap with IC/BPS, our consensus committee identified five main co‐morbid disorders: Endometriosis/Adenomyosis, Genito‐Pelvic Pain Penetration Disorder/Sexual Dysfunction, Overactive Pelvic Floor Muscles, Hormone‐ Associated Genitourinary Changes, Vulvodynia/Vestibulodynia.
Conclusion
While not exhaustive, this consensus highlights the most prevalent gynecologic co‐morbidities supported by current literature. Clinical evaluation should prioritize a detailed medical history and pelvic examination to identify these overlapping conditions. Future directions include developing a multidisciplinary diagnostic and treatment algorithm to guide clinicians—including urologists, gynecologists, urogynecologists, physical therapists—in comprehensive IC/BPS care.
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Details
Title
Role of Gynecologic Findings in Interstitial Cystitis/Bladder Pain Syndrome: A Consensus
Creators
Marie E. Sullivan - Wake Forest University
Amr El Haraki - Wake Forest University
Anna Padoa - Tel Aviv University
Katy Vincent - University of Oxford
Kristene E. Whitmore - Drexel University
Mauro Cervigni - Pontifícia Universidade Católica de São Paulo