Immunology Infectious Diseases Life Sciences & Biomedicine Science & Technology
Objective: Despite the efficacy of pre-exposure prophylaxis (PrEP) in reducing the risk of HIV infection, uptake remains low among many who are most vulnerable to HIV, such as Black and Latinx women. Interventions that target social networks to encourage at-risk women to initiate PrEP are underused. Design: This study used an egocentric network design and sampled Black/African American and Latinx women at risk of HIV as well as people from their social networks (N = 211) in a small, western city. Methods: Multivariable generalized linear mixed effects regression models investigated individual-level and network-level characteristics associated with likely future PrEP use. Results: PrEP awareness was low, but once informed, 36% considered themselves likely to take it in the future. Perceived risk of HIV, perceived barriers to HIV testing, and participation in a 12-step program increased odds of anticipated PrEP use. A higher proportion of friends in one's network decreased odds of future PrEP use, whereas a higher proportion of network members who tested regularly for HIV increased odds of future PrEP use. A marginally significant interaction was detected between proportion of friends in one's network and proportion of the network perceived to test for HIV regularly (ie, testing norms). When HIV testing norms were low, a higher proportion of friends in the network decreased odds of likely PrEP use. However, this effect was reversed in contexts with strong testing norms. Conclusion: Women who are interested in PrEP may be embedded within social and normative contexts that can foster or inhibit PrEP uptake.
Role of Social Networks and Social Norms in Future PrEP Use in a Racially Diverse Sample of At-Risk Women and Members of Their Social Networks
Creators
Laura M. Johnson - University of Nevada Reno
Harold D. Green - Indiana University
Brandon Koch - University of Nevada Reno
Jamila K. Stockman - University of California, San Diego
Marisa Felsher - Johns Hopkins Univ, Sch Med, Div Infect Dis, Baltimore, MD 21205 USA
Alexis M. Roth - Johns Hopkins Medicine
Karla D. Wagner - University of Nevada Reno
Publication Details
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, v 86(4), pp 422-429
Publisher
Lippincott Williams & Wilkins
Number of pages
8
Grant note
R01DA038185 / National Institute On Drug Abuse (NIDA) of the National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Drug Abuse (NIDA)
P30AI036214 / San Diego Center for AIDS Research
R21DA043417-02 / NIDA; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Drug Abuse (NIDA)
Resource Type
Journal article
Language
English
Academic Unit
Community Health and Prevention
Web of Science ID
WOS:000656627600011
Scopus ID
2-s2.0-85102222098
Other Identifier
991019169005204721
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