Journal article
Role of monotherapy with new antiepileptic drugs in the treatment of childhood epilepsy
Medicina (Buenos Aires), v 69(1)
01 Jan 2009
PMID: 19240007
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
In this paper we review the current information regarding the use of new antiepileptic drugs (AEDs) used as monotherapy in children. We specifically include the following AEDs: lamotrigine (Lamictal (R)), topiramate (Topamax (R)), zonisamide (Zonegran (R)), levetiracetarn (Keppra (R)), and oxcarbazepine (Trileptal (R)). All of these AEDs have a broad spectrum of action in the treatment of partial and generalized seizures. except Oxcarbazepine, which is effective only in partial seizures. It is unclear whether or not monotherapy with the new AEDs offers higher efficacy and/or lower side effects compared to classic AEDs (phenobarbital, phenytoin, carbamazepine, or valproate) thereby significantly improving the quality of life in children with epilepsy. More studies are needed to answer these questions.
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Details
- Title
- Role of monotherapy with new antiepileptic drugs in the treatment of childhood epilepsy
- Creators
- Ignacio Valencia - Drexel UniversityAgustin Legido - Drexel Univ, Neurol Sect, Dept Pediat, St Christophers Hosp Children,Coll Med, Philadelphia, PA 19134 USA
- Publication Details
- Medicina (Buenos Aires), v 69(1)
- Publisher
- Medicina (Buenos Aires)
- Number of pages
- 8
- Resource Type
- Journal article
- Language
- Spanish
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:000263883200012
- Scopus ID
- 2-s2.0-62149128533
- Other Identifier
- 991019169163904721
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- Web of Science research areas
- Clinical Neurology