Journal article
Sacral Neuromodulation: Determining Predictors of Success
UROLOGY, v 153, pp 124-128
Jul 2021
PMID: 32619594
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
OBJECTIVE To determine predictors of success for sacral neuromodulation in women with overactive bladder, urinary retention, and fecal incontinence. METHODS A retrospective chart review was performed on women who underwent a staged sacral neuromodulation implantation between 2007 and 2018. Clinical and procedural characteristics were recorded. Presence of intraoperative motor responses in either all 4 or <4 electrodes were used to group women. Endpoints included completion of stage II implant, tined lead revision, and patient-reported success. RESULTS In 198 women with a mean age of 62.9 years (SD+/- 14.7), completion of stage II implant occurred in 92.4% of women, and 83.3% of these women reported success at the first postoperative visit. Continued success at 6 months was reported in 70.3%. Lead revision was noted in 23.0%. Age >65 years (odds ratio [OR] = 0.2, 95% confidence interval [CI] = 0.06-0.8) and prior onabotulinumtoxinA (onaBoNT-A) (OR = 0.2, 95% CI = 0.06-0.9) were negative predictors for completion of stage II implant on multivariable analysis. Also, prior pelvic floor physical therapy was a significant negative predictor of postoperative patient-reported success on multivariable analysis (OR = 0.25, 95% CI = 0.1-0.6). There were no differences seen in women who had motor responses with either all 4 electrodes or <4 electrodes in any endpoint (P > .05). CONCLUSION Patient age >65 and history of prior onaBoNT-A were associated with failure to complete stage II implant. Women with prior pelvic floor physical therapy were less likely to report success after sacral neuromodulation. Motor responses in <4 electrodes during lead testing did not impact patient-reported success. (C) 2020 Elsevier Inc.
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Details
- Title
- Sacral Neuromodulation: Determining Predictors of Success
- Publication Details
- UROLOGY, v 153, pp 124-128
- Publisher
- ELSEVIER SCIENCE INC; NEW YORK
- Number of pages
- 4
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Drexel University
- Web of Science ID
- WOS:000684866100024
- Scopus ID
- 2-s2.0-85107618813
- Other Identifier
- 991021860668404721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Urology & Nephrology