Journal article
Safety and efficacy of a novel ultrasonic osteotome device in an ovine model
Journal of clinical neuroscience, v 18(11), pp 1528-1533
01 Nov 2011
PMID: 21917459
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The use of ultrasonic technology for bone removal offers the potential advantages over the use of traditional hand instruments or cutting burrs of more precise bone resection and reduced soft-tissue injury. While the use of modified ultrasonic aspirators has been described for bone removal in spinal surgery, none of these instruments has been systematically examined to evaluate safety and efficacy. Thus, we compared laminectomies using traditional instruments, and traditional instruments with an ultrasonic osteotome, in an ovine model. We used a combination of clinical examination, intra-operative and post-operative neuromonitoring and histological analysis to evaluate safety. The secondary endpoint of efficiency was assessed by examining operative times. No significant difference was found between groups in neurophysiology or the Tarlov clinical rating scale. Histology revealed inflammatory or reparative changes in 6/8 experimental animals and 2/4 control animals with a single section in an experimental animal revealing focal nerve root disruption and mild axonal loss. A single durotomy was noted in both the control and experimental groups. Operative time for the experimental group was significantly shorter than the operative time for the control group.
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Details
- Title
- Safety and efficacy of a novel ultrasonic osteotome device in an ovine model
- Creators
- Matthew R. Sanborn - Hospital of the University of PennsylvaniaJeffrey Balzer - University of PittsburghPeter C. Gerszten - University of PittsburghPatricia Karausky - University of PittsburghBoyle C. Cheng - University of PittsburghWilliam C. Welch - Hospital of the University of Pennsylvania
- Publication Details
- Journal of clinical neuroscience, v 18(11), pp 1528-1533
- Publisher
- Elsevier
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Surgery
- Web of Science ID
- WOS:000296402800024
- Scopus ID
- 2-s2.0-80053563941
- Other Identifier
- 991021930449204721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Neurosciences