Journal article
Salt as a catalyst in the mitochondria: returning cytochrome c to its native state after it misfolds on the surface of cardiolipin containing membranes
Chemical communications (Cambridge, England), v 50(28), pp 3674-3676
2014
PMID: 24394851
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Cytochrome c binding to cardiolipin receptors on the surface of TOCL/DOPC(20% : 80%) liposomes induces a conformational change, which is not reversible after the protein's dissociation at low ionic strength. Addition of 100 mM NaCl switches the protein back to its native state.
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Details
- Title
- Salt as a catalyst in the mitochondria: returning cytochrome c to its native state after it misfolds on the surface of cardiolipin containing membranes
- Creators
- Leah A Pandiscia - Department of Chemistry, Drexel University, Philadelphia, USAReinhard Schweitzer-Stenner - Department of Chemistry, Drexel University, Philadelphia, USA
- Publication Details
- Chemical communications (Cambridge, England), v 50(28), pp 3674-3676
- Publisher
- Royal Society of Chemistry
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Chemistry
- Web of Science ID
- WOS:000332927500006
- Scopus ID
- 2-s2.0-84901743083
- Other Identifier
- 991014878039704721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Chemistry, Multidisciplinary