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Scholarly literature review: management of neurocognitive late effects with stimulant medication
Journal article   Open access   Peer reviewed

Scholarly literature review: management of neurocognitive late effects with stimulant medication

Brian P Daly and Ronald T Brown
Journal of pediatric psychology, v 32(9), pp 1111-1126
Oct 2007
DOI: https://doi.org/10.1093/jpepsy/jsm012
PMID: 17442692
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1093/jpepsy/jsm012View
Published, Version of Record (VoR) Open

Abstract

Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Central Nervous System Stimulants - pharmacology Central Nervous System Stimulants - therapeutic use Brain Neoplasms - psychology Humans Precursor Cell Lymphoblastic Leukemia-Lymphoma - psychology Brain Neoplasms - drug therapy Cognition - drug effects Child
To examine the extant literature on stimulant drug therapy for survivors of childhood cancer during the late-effects period. A review of literature is provided on the mechanism of and cognitive toxicities for children and adolescents treated for acute lymphoblastic leukemia (ALL) and malignant brain tumors (BT) as well as the pharmacotherapy of stimulant medications, with a specific review of literature on the efficacy and safety of the stimulants for children with ALL and BT. Only four studies were found that have examined the effects of stimulant medication on the cognitive toxicities of childhood survivors of cancer during the late-effects period and only two of these investigations were controlled clinical trials. Findings suggest efficacy of the stimulants on parent and teacher ratings of attention and putative tasks of attention and executive functioning. Although there is some preliminary support for the efficacy and safety of the stimulants for survivors of ALL and BT, more research is needed concerning the long-term effects of the stimulants among cancer survivors.

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12 Record Views
20 citations in Web of Science
24 citations in Scopus

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Web of Science research areas
Psychology, Developmental
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