Journal article
Seasonal Variations in the Progression of Myopia in Children Enrolled in the Correction of Myopia Evaluation Trial
Investigative ophthalmology & visual science, v 55(2), pp 752-758
04 Feb 2014
PMID: 24408976
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
PURPOSE. To investigate monthly and seasonal variations in the progression of myopia in children enrolled in the Correction of Myopia Evaluation Trial (COMET).
METHODS. An ethnically diverse cohort of 469 myopic 6- to <12 year-old children was randomized to single vision or progressive addition lenses and followed for 3 years with 98.5% retention. Progression of myopia was measured semiannually by noncycloplegic autorefraction (Nidek ARK 700A) and annually by cycloplegic autorefraction, with the former measurements used in these analyses. The semiannual progression rate was calculated as (change in spherical equivalent refraction between two consecutive semiannual visits/number of days between the two visits) times 182.5. Months were categorized as the midpoint between two visit dates. Seasons were classified as winter (October through March) or summer (April through September). The seasonal difference was tested using a linear mixed model adjusting for demographic variables (age, sex, ethnicity), baseline refraction, and treatment group.
RESULTS. Data from 358 children (mean [+/- SD] age = 9.84 +/- 1.27 years; mean myopia = -2.54 +/- 0.84 diopters [D]) met the criteria for these analyses. Myopia progression varied systematically by month; it was slower in April through September than in the other months. Mean progression in winter was 0.35 +/- 0.34 D and in summer was 0.14 +/- 0.32 D, a statistically significant difference (0.21 D, P < 0.0001). The same seasonal pattern was found by age, sex, ethnicity (except in the small sample of Asians), lens type, and clinical center.
CONCLUSIONS. The slower progression of myopia found in summer is likely related to children's spending more time outdoors and fewer hours in school. The data have clinical implications regarding the time of year and the frequency with which myopic children have eye examinations and the need for precise timing of visits in clinical trials testing new myopia treatments.
Metrics
Details
- Title
- Seasonal Variations in the Progression of Myopia in Children Enrolled in the Correction of Myopia Evaluation Trial
- Creators
- Jane Gwiazda - New England College of OptometryLi Deng - New England College of OptometryRuth Manny - University of HoustonThomas T. Norton - University of AlabamaCOMET Study GrpMitchell Scheiman - Pennsylvania College of Optometry (PCO)
- Publication Details
- Investigative ophthalmology & visual science, v 55(2), pp 752-758
- Publisher
- Assoc Research Vision Ophthalmology Inc
- Number of pages
- 7
- Grant note
- U10EY011740 / NATIONAL EYE INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI) EY11756; EY11754; EY11805; EY11752; EY11740; EY11755 / National Eye Institute/National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pennsylvania College of Optometry (PCO)
- Web of Science ID
- WOS:000331891700017
- Scopus ID
- 2-s2.0-84893262929
- Other Identifier
- 991021900614104721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Ophthalmology