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Secondary aneurysmal bone cyst arising from polyostotic craniofacial fibrous dysplasia
Journal article - Includes Student Work   Open access   Peer reviewed

Secondary aneurysmal bone cyst arising from polyostotic craniofacial fibrous dysplasia

Niket Patel, Kiran Kumar Sailagundla, Essaki Rajulu, Shanmuga Jayanthan, Ganesh Rajagopal and Harpreet Singh Grewal
BJR case reports, v 11(5), uaaf047
01 Sep 2025
PMID: 40979182
url
https://doi.org/10.1093/bjrcr/uaaf047View
Published, Version of Record (VoR) Open

Abstract

Case Report
Fibrous dysplasia (FD) is a benign condition affecting osteoblasts, which fail to undergo proper differentiation and maturation, resulting in the replacement of normal osteoid matrix with ground glass fibrous tissue. Aneurysmal bone cyst (ABC) is a benign, expansile, lytic lesion characterized by multiple blood-filled cystic cavities containing haemorrhagic products at varying stages. Secondary ABC arising from craniofacial FD is extremely rare. To date, only 10 cases have been reported in the literature. This report highlights the clinical presentation, imaging findings, and histopathological confirmation of a secondary ABC in a patient with polyostotic craniofacial FD.

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