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Sedentary Behavior and Physical Function Decline in Older Women: Findings from the Women's Health Initiative
Journal article   Open access   Peer reviewed

Sedentary Behavior and Physical Function Decline in Older Women: Findings from the Women's Health Initiative

Rebecca Seguin, Michael LaMonte, Lesley Tinker, Jingmin Liu, Nancy Woods, Yvonne L Michael, Cheryl Bushnell and Andrea Z LaCroix
Journal of aging research, v 2012, pp 1-10
2012
PMID: 22675631
url
https://doi.org/10.1155/2012/271589View
Published, Version of Record (VoR) Open

Abstract

Sedentary behavior is associated with deleterious health outcomes. This study evaluated the association between sedentary time and physical function among postmenopausal women in the Women's Health Initiative Observational Study. Data for this prospective cohort study were collected between 1993–1998 (enrollment) and 2009, with an average of 12.3 follow-up years. Analyses included 61,609 women (aged 50–79 years at baseline). Sedentary time was estimated by questionnaire; physical function was measured using the RAND SF-36 physical function scale. Mixed-model analysis of repeated measures was used to estimate the relationship of sedentary time exposures and changes in physical function adjusting for relevant covariates. Compared to women reporting sedentary time of ≤6 hours/day, those with greater amounts of sedentary time (>6–8 hours/day, >8–11 hours/day, >11 hours/day) reported lower physical function between baseline and follow up (coefficient = −0.78, CI = −0.98, −0.57, −1.48, CI = −1.71, −1.25, −3.13, and CI = −3.36, −2.89, respectivelyP<0.001). Sedentary time was strongly associated with diminished physical function and most pronounced among older women and those reporting the greatest sedentary time. Maintaining physical function with age may be improved by pairing messages to limit sedentary activities with those promoting recommended levels of physical activity.

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