Journal article
Selectivity of polymer-coated alumina stationary phases for reversed-phase liquid chromatography. Part 1. Methylene group selectivity
Analyst, v 119(6), pp 133-1314
1994
Abstract
The methylene selectivity of various polymer-coated alumina columns [polybutadiene (PBD), and polymeric CN and C
18
phases] are compared with those for three conventional silica bonded-phase C
18
columns. Retention and selectivity data were obtained using hydroorganic mixtures of acetonitrile and methanol for selected aromatic and aliphatic compounds, including
n
-2-ketones (C
4
-C
9
),
n
-alkylphenones (C
8
-C
11
),
n
-alkylbenzenes (C
7
-C
15
), and
n
-alkanes (C
5
-C
7
). For a given mobile phase, the polymer-coated alumina columns and silica based C
18
columns exhibited similar methylene selectivity, although the alumina columns were much less retentive. The latter characteristic suggests a potentially important advantage of polymer-coated aluminas, namely that for a given homologous series it should be possible to employ a weaker mobile phase on the polymer-coated columns, thereby achieving higher methylene selectivity with equivalent retention. The inherent selectivity advantage of the different polymer-coated aluminas may be especially important when separation selectivity is to be optimized by changing columns.
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15 citations in Scopus
Details
- Title
- Selectivity of polymer-coated alumina stationary phases for reversed-phase liquid chromatography. Part 1. Methylene group selectivity
- Creators
- Rene V ArenasJoe P Foley
- Publication Details
- Analyst, v 119(6), pp 133-1314
- Publisher
- Royal Society of Chemistry
- Number of pages
- 12
- Resource Type
- Journal article
- Academic Unit
- Chemistry
- Scopus ID
- 2-s2.0-0001289271
- Other Identifier
- 991021906171304721