Logo image
Back
Self-Reported Stroke Risk Stratification: Reasons for Geographic and Racial Differences in Stroke Study
Journal article   Open access   Peer reviewed

Self-Reported Stroke Risk Stratification: Reasons for Geographic and Racial Differences in Stroke Study

George Howard, Leslie A McClure, Claudia S Moy, Virginia J Howard, Suzanne E Judd, Ya Yuan, D Leann Long, Paul Muntner, Monika M Safford and Dawn O Kleindorfer
Stroke (1970), v 48(7), pp 1737-1743
Jul 2017
DOI: https://doi.org/10.1161/STROKEAHA.117.016757
PMID: 28526763
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://europepmc.org/articles/pmc5493147View
Accepted (AM),  Open
url
https://doi.org/10.1161/STROKEAHA.117.016757View
Published, Version of Record (VoR) Open

Abstract

Aged Aged, 80 and over Blacks Cohort Studies Female Follow-Up Studies Humans Male Middle Aged Racial Groups Random Allocation Risk Assessment - methods Risk Assessment - standards Self Report - standards Stroke - diagnosis Stroke - epidemiology United States - epidemiology Whites
The standard for stroke risk stratification is the Framingham Stroke Risk Function (FSRF), an equation requiring an examination for blood pressure assessment, venipuncture for glucose assessment, and ECG to determine atrial fibrillation and heart disease. We assess a self-reported stroke risk function (SRSRF) to stratify stroke risk in comparison to the FSRF. Participants from the REGARDS study (Reasons for Geographic and Racial Differences in Stroke) were evaluated at baseline and followed for incident stroke. The FSRF was calculated using directly assessed stroke risk factors. The SRSRF was calculated from 13 self-reported questions to exclude those with prevalent stroke and assess stroke risk. Proportional hazards analysis was used to assess incident stroke risk using the FSRF and SRSRF. Over an average 8.2-year follow-up, 939 of 23 983 participants had a stroke. The FSRF and SRSRF produced highly correlated risk scores ( =0.852; 95% confidence interval, 0.849-0.856); however, the SRSRF had higher discrimination of stroke risk than the FSRF (c =0.7266; 95% confidence interval, 0.7076-0.7457; c =0.7075; 95% confidence interval, 0.6877-0.7273; =0.0038). The 10-year stroke risk in the highest decile of predicted risk was 11.1% for the FSRF and 13.4% for the SRSRF. A simple self-reported questionnaire can be used to identify those at high risk for stroke better than the gold standard FSRF. This instrument can be used clinically to easily identify individuals at high risk for stroke and also scientifically to identify a subpopulation enriched for stroke risk.

Metrics

21 Record Views
15 citations in Web of Science
12 citations in Scopus

Details

UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

InCites Highlights

Data related to this publication, from InCites Benchmarking & Analytics tool:

Collaboration types
Domestic collaboration
Web of Science research areas
Clinical Neurology
Peripheral Vascular Disease
Logo image