Journal article
Semiconductor laser insert with uniform illumination for use in photodynamic therapy
Applied optics (2004), v 44(24), pp 5055-5068
20 Aug 2005
PMID: 16121790
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
A low-cost semiconductor red laser light delivery system for esophagus cancer treatment is presented. The system is small enough for insertion into the patient's body. Scattering elements with nanoscale particles are used to achieve uniform illumination. The scattering element optimization calculations, with Mie theory, provide scattering and absorption efficiency factors for scattering particles composed of various materials. The possibility of using randomly deformed spheres and composite particles instead of perfect spheres is analyzed using an extension to Mie theory. The measured radiation pattern from a prototype light delivery system fabricated using these design criteria shows reasonable agreement with the theoretically predicted pattern.
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Details
- Title
- Semiconductor laser insert with uniform illumination for use in photodynamic therapy
- Creators
- Ivan Charamisinau - Southern Methodist UniversityGemunu Happawana - Southern Methodist UniversityGary Evans - Southern Methodist UniversityArye Rosen - Drexel UniversityRichard A Hsi - Hospital of the University of PennsylvaniaDavid Bour - Agilent TechnologiesAaron J Rosen - Pathology (and Laboratory Medicine)
- Publication Details
- Applied optics (2004), v 44(24), pp 5055-5068
- Publisher
- Optica (OSA)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Electrical and Computer Engineering; Pathology (and Laboratory Medicine)
- Web of Science ID
- WOS:000231292500008
- Scopus ID
- 2-s2.0-25444463314
- Other Identifier
- 991019168959204721
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- Collaboration types
- Industry collaboration
- Domestic collaboration
- Web of Science research areas
- Optics