Journal article
Serum androstanediol glucuronide in women with facial hirsutism
Journal of the American Academy of Dermatology, v 26(3), pp 411-414
1992
PMID: 1564146
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Abstract
Background: Measurement of serum 5α-androstane-3α,17β-diol glucuronide (3α-diol G) has been proposed as a useful biochemical marker of peripheral androgen metabolism. Is 3α-diol G a useful biochemical marker of peripheral androgen metabolism and does it correlate with degree of facial hirsutism?
Objective: Our purpose was to assess possible correlation between serum 3α-diol G and degree of facial hirsutism and to compare serum 3α-diol G levels with levels of other commonly measured serum androgens.
Methods: Twenty-three consecutive women with facial hirsutism were studied, and serum concentrations of 3α-diol G, testosterone (total, free, and biologically active portions), dehydroepiandrosterone sulfate, and androstenedione were measured.
Results: There was no correlation between serum 3α-diol G levels and degree of facial hirsutism. There was a correlation between levels of 3α-diol G and dehydroepiandrosterone sulfate (
p < 0.01), biologically active testosterone (
p = 0.01), free testosterone (
p < 0.02), and androstenedione (
p < 0.05).
Conclusion: Serum 3α-diol G concentrations have no correlation with degree of facial hirsutism and do not provide additional information over the commonly measured androgens.
Metrics
Details
- Title
- Serum androstanediol glucuronide in women with facial hirsutism
- Creators
- Karl Salman - Hahnemann University HospitalRichard L. Spielvogel - Hahnemann University HospitalLeon H. Shulman - Hahnemann University HospitalJeffrey L. Miller - Hahnemann University HospitalRaymond E. Vanderlinde - Hahnemann University HospitalLeslie I. Rose - Hahnemann University HospitalJacob L Miller - Management
- Publication Details
- Journal of the American Academy of Dermatology, v 26(3), pp 411-414
- Publisher
- Mosby, Inc
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Management
- Web of Science ID
- WOS:A1992HF65900007
- Scopus ID
- 2-s2.0-0026575582
- Other Identifier
- 991019174516704721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Dermatology