Set-Shifting Among Adolescents With Bulimic Spectrum Eating Disorders
Alison M. Darcy, Kathleen Kara Fitzpatrick, Danielle Colborn, Stephanie Manasse, Nandini Datta, Vandana Aspen, Colleen Stiles Shields, Daniel Le Grange and James Lock
Life Sciences & Biomedicine Psychiatry Psychology Psychology, Multidisciplinary Science & Technology Social Sciences
Objective: Set-shifting difficulties are observed among adults with bulimia nervosa (BN). This study aimed to assess whether adolescents with BN and BN spectrum eating disorders exhibit set-shifting problems relative to healthy controls. Methods: Neurocognitive data from 23 adolescents with BN were compared with those from 31 adolescents with BN-type eating disorder not otherwise specified and 22 healthy controls on various measures of set-shifting (Trail Making Task [shift task], Color-Word Interference, Wisconsin Card Sorting Test, and Brixton Spatial Anticipation Task). Results: No significant differences in set-shilling tasks were found among groups (p >.35), and effect sizes were small (Cohen f < 0.17). Conclusions: Cognitive inflexibility may develop over time because of the eating disorder, although it is possible that there is a subset of individuals in whom early neurocognitive difficulty may result in a longer illness trajectory. Future research should investigate the existence of neurocognitive taxons in larger samples and use longitudinal designs to fully explore biomarkers and illness effects. Trial Registration: clinicaltrials.gov NCT00879151.
Set-Shifting Among Adolescents With Bulimic Spectrum Eating Disorders
Creators
Alison M. Darcy - Stanford University
Kathleen Kara Fitzpatrick - Stanford University
Danielle Colborn - Stanford University
Stephanie Manasse - Stanford University
Nandini Datta - Stanford University
Vandana Aspen - Stanford University
Colleen Stiles Shields - University of Chicago
Daniel Le Grange - University of Chicago
James Lock - Stanford University
Publication Details
Psychosomatic medicine, v 74(8), pp 869-872
Publisher
Lippincott Williams & Wilkins
Number of pages
4
Grant note
Davis Foundation
R01 MH079979; NTH SPO 37129 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
R01MH079978 / NATIONAL INSTITUTE OF MENTAL HEALTH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH)
Resource Type
Journal article
Language
English
Academic Unit
Center for Weight, Eating and Lifestyle Science (WELL) [Historical]
Web of Science ID
WOS:000310047800011
Scopus ID
2-s2.0-84867269043
Other Identifier
991020100064004721
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