Journal article
Severe Pulmonary Hemorrhage in a Neonate With Hypoxic Ischemic Encephalopathy and Sepsis Managed on Extracorporeal Membrane Oxygenation
ASAIO journal (1992), v 68(6), pp e106-e109
01 Jun 2022
PMID: 34264871
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Pulmonary hemorrhage (PH) is an infrequent and potentially fatal event in term neonates. Reports of successful management of PH on extracorporeal membrane oxygenation (ECMO) are limited, given the accentuated risk of mortality imposed by the use of heparin to prevent thrombosis on ECMO. We present a case of a term neonate with hypoxic ischemic encephalopathy undergoing controlled hypothermia who developed hypoxic respiratory failure, hemodynamic instability, Enterobacter cloacae pneumonia and sepsis complicated by severe PH who required support with veno-arterial ECMO. We describe the therapeutic strategies used on veno-arterial ECMO to successfully manage this infant, including clamping the endotracheal tube, aggressive correction of coagulopathy, and use of dornase alfa, as well as elaborate on the subtle changes in ECMO parameters during the run that preceded worsening pneumonia with sepsis.
Metrics
Details
- Title
- Severe Pulmonary Hemorrhage in a Neonate With Hypoxic Ischemic Encephalopathy and Sepsis Managed on Extracorporeal Membrane Oxygenation
- Creators
- Vilmaris Quinones Cardona - From the Division of Neonatology, Department of Pediatrics, St Christopher's Hospital for Children, Philadelphia, Pennsylvania Department of Pediatrics, Drexel University College of Medicine, Philadelphia, Pennsylvania.Swosti Joshi - Drexel UniversityDaniel Conway - Drexel UniversityOgechukwu R Menkiti - Drexel University
- Publication Details
- ASAIO journal (1992), v 68(6), pp e106-e109
- Publisher
- Lippincott
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:000804311100005
- Scopus ID
- 2-s2.0-85127580642
- Other Identifier
- 991019167429904721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Engineering, Biomedical
- Transplantation