Journal article
Short-Term Outcomes of Bimatoprost Sustained-Release Intracameral Implant in Glaucoma
JOURNAL OF GLAUCOMA, v 32(9), p738
Sep 2023
PMID: 37523637
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Precis: This retrospective study found a statistically significant reduction in mean intraocular pressure (IOP) and the number of medications after intracameral Bimatoprost sustained release (SR) injection in patients with glaucoma. A history of selective laser trabeculoplasty (SLT) did not impact treatment outcomes. Purpose: To determine outcomes of Bimatoprost SR on IOP and the number of topical IOP-lowering medications in patients with glaucoma. A secondary objective was to determine the outcomes of Bimatoprost SR in patients with a prior history of SLT. Methods: Retrospective case series. One hundred eighteen eyes from 84 patients that received Bimatoprost SR by 6 glaucoma specialists at Wills Eye Hospital from March 2020 to September 2021 were examined. The intervention was a single injection of intracameral Bimatoprost SR. The main outcome measures included IOP and the number of medications. Results: The most recent mean follow-up time for all eyes was 27.8 +/- 18.6 weeks. The mean posttreatment IOP at the most recent follow-up of 16.6 +/- 5.3 mm Hg was significantly lower than the mean under-therapy pretreatment IOP of 18.5 +/- 5.7 mm Hg for all eyes (P < 0.01). The mean posttreatment number of medications at the most recent follow-up of 1.3 +/- 1.3 decreased compared with the number of pretreatment medications of 2.1 +/- 1.4 for all eyes (P < 0.01). Analysis of multilevel models controlling for demographic variables demonstrated a statistically significant reduction in IOP and number of medications posttreatment (P < 0.01). A prior history of SLT (n = 54) had no impact on treatment for both IOP and the number of medications (P > 0.1 for both). Conclusions: Intracameral Bimatoprost SR reduced IOP and decreased the number of medications. Prior history of SLT did not impact Bimatoprost SR treatment outcomes.
Metrics
Details
- Title
- Short-Term Outcomes of Bimatoprost Sustained-Release Intracameral Implant in Glaucoma
- Publication Details
- JOURNAL OF GLAUCOMA, v 32(9), p738
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS; PHILADELPHIA
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Drexel University
- Web of Science ID
- WOS:001057981000006
- Scopus ID
- 2-s2.0-85169175168
- Other Identifier
- 991021861295404721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Ophthalmology