Journal article
Simple Strategy to Functionalize Polymeric Substrates via Surface-Initiated ATRP for Biomedical Applications
Langmuir, v 29(5), pp 1541-1550
05 Feb 2013
PMID: 23259848
Abstract
The functionalization of polymer surfaces via surface-initiated atom transfer radical polymerization (ATRP) is of crucial importance to prepare various functional materials. It is generally complicated to conduct ATRP on different organic material surfaces. In this work, a facile photoinduced one-step method was first developed for the covalent immobilization of ATRP initiators on the C-H group-containing substrates such as biaxially oriented polypropylene (BOPP). The C-H bonds of precise location of inert polymer surfaces were readily transferred to bromoalkyl initiator, followed by ATRP of 2-(dimethylamino)ethyl methacrylate (DMAEMA) and glycidyl methacrylate (GMA), respectively, to produce the resultant patterned BOPP-g-P(DMAEMA) and BOPP-g-P(GMA) films. The epoxy groups of the P(GMA) microdomains can be aminated for covalently coupling IgG, while the P(DMAEMA) microdomains were used for immobilizing IgG via electronic interactions. The resultant IgG-coupled microdomains could interact with the corresponding target proteins, anti-IgG.
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Details
- Title
- Simple Strategy to Functionalize Polymeric Substrates via Surface-Initiated ATRP for Biomedical Applications
- Creators
- C. Y. Li - Resource (United States)F. J. Xu - Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Key Lab Carbon Fiber & Funct Polymers, Minist Educ,Coll Mat Sci & Engn, Beijing 100029, Peoples R ChinaW. T. Yang - Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Key Lab Carbon Fiber & Funct Polymers, Minist Educ,Coll Mat Sci & Engn, Beijing 100029, Peoples R China
- Publication Details
- Langmuir, v 29(5), pp 1541-1550
- Publisher
- American Chemical Society; Washington, DC
- Number of pages
- 10
- Grant note
- 51033001; 51221002 / NSFC; National Natural Science Foundation of China (NSFC) EP/H04986X/1 / EPSRC; UK Research & Innovation (UKRI); Engineering & Physical Sciences Research Council (EPSRC) EP/H04986X/1 / Engineering and Physical Sciences Research Council; UK Research & Innovation (UKRI); Engineering & Physical Sciences Research Council (EPSRC) 2009AA03Z325 / National High Technology Research and Development Program (863 Program); National High Technology Research and Development Program of China
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Materials Science and Engineering
- Web of Science ID
- WOS:000314676000027
- Scopus ID
- 2-s2.0-84873394614
- Other Identifier
- 991019196701004721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Chemistry, Multidisciplinary
- Chemistry, Physical
- Materials Science, Multidisciplinary