Journal article
Single-Dose Regimen of Cefonicid for the Treatment of Uncomplicated Infections of the Lower Urinary Tract
Clinical infectious diseases, v 6(Supplement-4), pp S844-S846
Nov 1984
PMID: 6395274
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Fifty-three women with symptoms of lower urinary tract infection were randomly assigned to treatment with cefonicid administered intramuscularly in a single l-g dose or to treatment with 500 mg of amoxicillin administered orally three times a day for five to seven days. Urine cultures were obtained before therapy and again at five to 18 days and six to seven weeks after termination of therapy. Forty-one patients had ⩾2 × 104 colony-forming units (cfu)/ml of catheterized urine or ⩾105 cfu/ml of midstream urine. In the cefonicid-treated group, 19 (90%) of 21 patients demonstrated bacteriologic cure at early follow-up. Of the 18 patients seen at late follow-up, 15 were cured and three were reinfected. One patient was lost to late follow-up. In the amoxicillin-treated group, 16 (80%) of 20 patients demonstrated bacteriologic cure at early follow-up. Of the 15 patients available at late follow-up, 14 were cured and one was reinfected. One patient was lost to late follow-up. Cefonicid is an effective single-dose agent in uncomplicated lower urinary tract infection.
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Details
- Title
- Single-Dose Regimen of Cefonicid for the Treatment of Uncomplicated Infections of the Lower Urinary Tract
- Creators
- S. I. Morgan - Department of Internal Medicine, Infectious Disease Section, New Orleans, Louisiana, Philadelphia, PennsylvaniaR. E. Pontzer - Department of Internal Medicine, Infectious Disease Section, New Orleans, Louisiana, Philadelphia, PennsylvaniaL. M. Cortez - Department of Internal Medicine, Infectious Disease Section, New Orleans, Louisiana, Philadelphia, PennsylvaniaS. L. Guice - Department of Internal Medicine, Infectious Disease Section, New Orleans, Louisiana, Philadelphia, PennsylvaniaW. Brannan - Department of Internal Medicine, Infectious Disease Section, New Orleans, Louisiana, Philadelphia, PennsylvaniaR. E. Krieger - Department of Internal Medicine, Infectious Disease Section, New Orleans, Louisiana, Philadelphia, PennsylvaniaW. McNamee - Department of Internal Medicine, Infectious Disease Section, New Orleans, Louisiana, Philadelphia, PennsylvaniaJ. A. Boscia - Department of Internal Medicine, Infectious Disease Section, New Orleans, Louisiana, Philadelphia, PennsylvaniaM. E. Levison - Department of Internal Medicine, Infectious Disease Section, New Orleans, Louisiana, Philadelphia, PennsylvaniaD. Kaye - Department of Internal Medicine, Infectious Disease Section, New Orleans, Louisiana, Philadelphia, Pennsylvania
- Publication Details
- Clinical infectious diseases, v 6(Supplement-4), pp S844-S846
- Publisher
- The University of Chicago Press
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Medicine (Graduate)
- Web of Science ID
- WOS:A1984TW03900011
- Scopus ID
- 2-s2.0-0021531133
- Other Identifier
- 991019184065004721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Immunology
- Microbiology