Journal article
Sinonasal Anatomic Variants in Allergic Fungal Rhinosinusitis
American journal of rhinology & allergy, v 35(5), pp 574-577
Sep 2021
PMID: 33283537
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background
The pathophysiology of allergic fungal rhinosinusitis (AFRS) is not well understood.
Objectives
To study the incidence of sinonasal anatomic variants (AVs) in AFRS.
Methods
Retrospective cohort study. Patients with AFRS presenting to our clinic from 2008 to 2018 were reviewed for laterality of the disease. Patients with unilateral involvement were further studied for AV presence by reviewing their preoperative sinus CT scan at original presentation. Each patient’s uninvolved side served as its own control. AVs studied include agger nasi (AN), Haller’s cells (HC), concha bullosa (CB) and supraorbital ethmoid cells (SOEC).
Results
A total of 155 patients with AFRS were identified. 30 patients (19.3%) had unilateral disease involvement. Of these, 16 patients had left sided and 14 patients had right sided disease. AV were present in 26 of the 30 AFRS sides (86.7%) and in 21 of the 30 healthy sides (70%), (chi squared = 2.45, p = 0.117). CB were present in 12 of 30 AFRS sides (40%) and only in 1 of 30 healthy sides (3%), (chi squared = 11.88, p = 0.0006). The presence of HC was more common in the AFRS vs healthy sides (7 of 30, 23.3% vs 2 of 30, 6.7%, respectively, p = 0.071). AN and SOEC presence was similar in both AFRS and healthy sides (p = 0.598 and p = 0.718 respectively).
Conclusion
AV are more common on the sides with AFRS compared to healthy sides, with the presence of CB reaching unquestionable statistical significance. Further study is needed to determine the possible association of AV, especially concha bullosa, with the pathophysiology of AFRS.
Metrics
Details
- Title
- Sinonasal Anatomic Variants in Allergic Fungal Rhinosinusitis
- Creators
- Chadi A. Makary - University of West VirginiaBrock Parman - Augusta UniversityBrittany Gill - Augusta UniversityAykut Unsal - Drexel UniversityThomas Holmes - Augusta UniversityCamilo Reyes - Augusta UniversityStilianos E. Kountakis - Augusta University
- Publication Details
- American journal of rhinology & allergy, v 35(5), pp 574-577
- Publisher
- Sage
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Otolaryngology (and Head and Neck Surgery)
- Web of Science ID
- WOS:000641100400001
- Scopus ID
- 2-s2.0-85097263759
- Other Identifier
- 991019169577104721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Otorhinolaryngology