Journal article
Skeletal muscle myosin II structure and function
Exercise and sport sciences reviews, v 27, pp 63-77
1999
PMID: 10791014
Abstract
Recent experimental advances in structural biology, biophysics, and molecular biology have dramatically increased our understanding of the molecular mechanism of muscle contraction, as well as the assembly of myosin filaments. Future studies are required to detail, for example, the molecular cause of the conformational change during the power stroke and ATP hydrolysis, as well as the nature of the communication between nucleotide and actin binding sites. Based on the structural and functional homology between myosin and other molecular motors, these findings have implications not only for understanding muscle contraction, but for understanding numerous aspects of motility in all cellular systems as well.
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Details
- Title
- Skeletal muscle myosin II structure and function
- Creators
- G J Lutz - Department of Orthopaedics, University of California at San Diego School of Medicine, USAR L Lieber
- Publication Details
- Exercise and sport sciences reviews, v 27, pp 63-77
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Biochemistry and Molecular Biology
- Scopus ID
- 2-s2.0-0033287622
- Other Identifier
- 991021463556404721