Files and links (1)
Published, Version of Record (VoR)Open Access (License Unspecified), Open
Journal article
Sleep Duration and Quality in Relation to Autonomic Nervous System Measures: The Multi-Ethnic Study of Atherosclerosis (MESA)
Sleep (New York, N.Y.), v 39(11), pp 1927-1926
01 Nov 2016
PMID: 27568797
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Short sleep duration and poor sleep quality are associated with adverse cardiovascular outcomes. Potential pathophysiological mechanisms include sleep-associated alterations in the autonomic nervous system. The objective of this study was to examine the associations of shorter sleep duration and poorer sleep quality with markers of autonomic tone: heart rate (HR), high-frequency HR variability (HF-HRV) and salivary amylase.
Cross-sectional analysis of data from actigraphy-based measures of sleep duration and efficiency and responses to a challenge protocol obtained from 527 adult participants in the Multi-Ethnic Study of Atherosclerosis.
Participants who slept fewer than 6 h per night (compared to those who slept 7 h or more per night) had higher baseline HR (fully adjusted model 0.05 log beats/min, 95% confidence interval [CI] 0.01, 0.09) and greater HR orthostatic reactivity (fully adjusted model 0.02 log beats/min, 95% CI 0.002, 0.023). Participants who slept 6 to less than 7 h/night (compared to those who slept 7 h or more per night) had lower baseline HF-HRV (fully adjusted model -0.31 log msec
, 95% CI -0.60, -0.14). Participants with low sleep efficiency had lower baseline HF-HRV than those with higher sleep efficiency (fully adjusted model -0.59 log msec
, 95% CI -1.03, -0.15). Participants with low sleep efficiency had higher baseline levels of amylase than those with higher sleep efficiency (fully adjusted model 0.45 log U/mL, 95% CI 0.04, 0.86).
Short sleep duration, low sleep efficiency, and insomnia combined with short sleep duration were associated with markers of autonomic tone that indicate lower levels of cardiac parasympathetic (vagal) tone and/or higher levels of sympathetic tone.
Metrics
Details
- Title
- Sleep Duration and Quality in Relation to Autonomic Nervous System Measures: The Multi-Ethnic Study of Atherosclerosis (MESA)
- Creators
- Cecilia Castro-Diehl - Columbia UniversityAna V Diez Roux - Drexel UniversitySusan Redline - Beth Israel Deaconess Medical CenterTeresa Seeman - University of California, Los AngelesPaula McKinley - University of California, Los AngelesRichard Sloan - Columbia UniversitySteven Shea - Columbia University
- Publication Details
- Sleep (New York, N.Y.), v 39(11), pp 1927-1926
- Grant note
- R01 HL098433 / NHLBI NIH HHS N01HC95169 / NHLBI NIH HHS N01HC95161 / NHLBI NIH HHS N01HC95164 / NHLBI NIH HHS N01HC95160 / NHLBI NIH HHS N01HC95167 / NHLBI NIH HHS N01HC95159 / NHLBI NIH HHS N01HC95163 / NHLBI NIH HHS N01HC95166 / NHLBI NIH HHS N01HC95168 / NHLBI NIH HHS UL1 TR000040 / NCATS NIH HHS UL1 TR001079 / NCATS NIH HHS N01HC95165 / NHLBI NIH HHS N01HC95162 / NHLBI NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative; Family (Community and Preventive) Medicine
- Web of Science ID
- WOS:000388930800004
- Scopus ID
- 2-s2.0-84995550130
- Other Identifier
- 991019167876904721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Neurosciences