Journal article
Slow-5 dynamic functional connectivity reflects the capacity to sustain cognitive performance during pain
NeuroImage (Orlando, Fla.), v 157
15 Aug 2017
PMID: 28583880
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Some individuals are more distracted by pain during a cognitive task than others, representing poor pain coping. We have characterized individuals as A-type (attention dominates) or P-type (pain dominates) based on how pain interferes with task speed. The ability to optimize behavior during pain may relate to the flexibility in communication at rest between the dorsolateral prefrontal cortex (DLPFC) of the executive control network, and the anterior mid-cingulate cortex (aMCC) of the salience network (SN) - regions involved in cognitive-interference. The aMCC and aIns (SN hub) also signify pain salience; flexible communication at rest between them possibly allowing prioritizing task performance during pain. We tested the hypotheses that pain-induced changes in task performance are related to resting-state dynamic functional connectivity (dFC) between these region pairs (DLPFC-aMCC; aMCC-aIns). We found that 1) pain reduces task consistency/speed in P-type individuals, but enhances performance in A-type individuals, 2) task consistency is related to the FC dynamics within DLPFC-aMCC and aMCC-aIns pairs, 3) brain-behavior relationships are driven by dFC within the slow-5 (0.01-0.027Hz) frequency band, and 4) dFC across the brain decreases at higher frequencies. Our findings point to neural communication dynamics at rest as being associated with prioritizing task performance over pain.
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Details
- Title
- Slow-5 dynamic functional connectivity reflects the capacity to sustain cognitive performance during pain
- Creators
- J C Cheng - University of TorontoR L Bosma - Toronto Western HospitalK S Hemington - University of TorontoA Kucyi - Stanford UniversityM A Lindquist - Johns Hopkins UniversityK D Davis - Toronto Western Hospital
- Publication Details
- NeuroImage (Orlando, Fla.), v 157
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychological and Brain Sciences (Psychology)
- Web of Science ID
- WOS:000410539800006
- Scopus ID
- 2-s2.0-85020227341
- Other Identifier
- 991021463706504721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Neuroimaging
- Neurosciences
- Radiology, Nuclear Medicine & Medical Imaging